Haplotype inference algorithms in Pedigrees
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2.9 years ago
S. Roa ▴ 10

Hello everyone!

I have a complex cattle pedigree in a .ped file, plink formatted, and I succesfully ran it in PedPhase. Pedigree: 1 family, 79 individuals, 40 founders, 50 SNP's.

I need to run that file in other algorithms for phasing, like Beagle, ShapeIt, or Whatshap. I'm a really beginner and would like some guidance on how to proceed, as I only have the .ped file. Can I run the other algorithms with just the .ped file? (I don't have the .map file)

In case it is possible, how can I convert the .ped file to beagle, or vcf format? I need to compare accuracy and run time of several algorithms.

I would really appreciate any guidance! Thank you for your help!

algorithms pedigree inference snps haplotype • 426 views
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