Deleted:Is WGS reliable for larges indels and duplication?
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4.0 years ago
vpsev3 ▴ 20

I came across this site https://www.centogene.com/diagnostics/whole-genome-sequencing-with-centogenome.html

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Are these low sensitivity rates related to an alignment problem?

I was wondering if, for example, PE150bp shotgun sequencing with 30X depth could detect these variants (like a 22q11.3 microduplication) with higher confidence.

sequencing • 1.1k views
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