Cut-off value from qvalue package R for Manhattan plot
0
0
Entering edit mode
2.8 years ago
b.g.tamang ▴ 20

Hi all, I am trying to plot manhattan plot from my GWAS object from rrBLUP. rrBLUP does display Manhattan plots with significant threshold line using qvalue package from Bioconductor. I am instead trying to make my own custom Manhattan plot (using qqman R package) since it is a lot customizable with significant threshold line. For that I am using the same qvalue package as follows:

qobj<- qvalue (p, fdr.level = 0.05)

The qobj has following components:

names (qobj)

[1] "call" "pi0" "qvalues" "pvalues" "lfdr" "fdr.level"
[7] "significant" "pi0.lambda" "lambda" "pi0.smooth"

I can use "significant" component for downstream analysis. But how can I get that single significant threshold value to plot in my custom Manhattan plot?

Your help is much appreciated.

Thank you,

GWAS qvalue threshold significant plot manhattan rrBLUP • 782 views
ADD COMMENT

Login before adding your answer.

Traffic: 1332 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6