Is it possible to analyze only a subset of genes from different microarray datasets?

Question

[iltan1]

Hi all! I am new here. I am also new to in-silico analyses. This is my first post. I have been reading a lot of previous posts re R and microarray data analyses, which have been very helpful. So far, the microarray datasets I have compiled all have Affymetrix platforms (various though). I plan to include different datasets and focus only on genes associated with glucose metabolism (particularly glycolysis, Krebs, and oxidative phosphorylation) and check the clustering of biological samples using PCA. I would like to know if this is possible and if this goal is okay to pursue. I would appreciate all your comments and suggestions. Thanks

Irene