Functional annotation with VEP: combine the same variant between the samples in the same line (question)
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2.4 years ago
Adham • 0

Dear colleagues

I used VEP to annotate a multisamples vcf file, but I get separate lines of the same variant, which corresponds to each sample.

here is an example of output

Location         Allele       IND     ZYG
chr1:27868305-27868306  A        sample1   HET
chr1:27868305-27868306  A        sample2   HOM
chr1:27868305-27868306  A        sample3   HET

I would like to get a single row for each variant, like this:

    Location         Allele               IND               ZYG
chr1:27868305-27868306  A        sample1,sample2,sample3   HET,HOM,HET

Or

Location          Allele      sample1  sample2   sample3
chr1:27868305-27868306  A         HET        HOM        HET

Do you have an idea ?

output VEP Annotation • 509 views
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