Using reverse-complement or just complement of SILVA database to filter rRNA from metatranscriptomics

Question

[Mort]

I want to use SILVA database to filter rRNA from metatranscriptomics.

The nucleobases in the SILVA fasta file are A, U, C and G. Therefore, before indexing the SILVA fasta file, should I get the reverse-complement or just complement of the SILVA fasta file?

Thanks in advance!

Mort