Find most mutated genes in TCGA and perform RNA SEQ

Question

[BioNerd]

I have a data set that uses TCGA data and I want to find the 10 most mutated genes by counting how many times each gene is mutated (Mutated==1) and then I want to find which genes are more expressed using RNA seq data. Can i have some guidance please because I am new to this. Thank you.

Answer 1

[shiyang_bio]

If you are not familiar with bioinformatics, I recommend using cBioportal for your analysis. You can lean how to use cBioportal according to the guidance on its website. It can meet all your requirements.