Hi all,
I am currently working on a differential transcript usage analysis and I am using DRIMSeq
Instead of the dispersion estimate for a gene like in differential gen expression they estimate the precision parameter which is according to the pdf inversely related to the dispersion. So if dispersion goes up precision goes down. So far so good.
However, I don't seem to understand this concept fully since when I look at my results, I have genes with a precision of 140 and a mean expression of 97 which I cannot really judge or understand that value range. For a dispersion estimate I would have assumed a range of 0 to 1 or 0 to 100. But maybe I am misunderstanding something here.
Could maybe someone explain to me the concept of DRIMSeq's precision and its value range ?
Thanks !
