any tool to plot the fragment profile for ctDNA samples?
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2.2 years ago
J.F.Jiang ▴ 920

Hi all,

Fragment size of ctDNA offered us another dimension data, since cfDNA from tumors tended to smaller than normal ones.

As displayed in "Genome-wide cell-free DNA fragmentation in patients with cancer", fig.2 offered me a direct information (or comparison) between normal and tumors.

enter image description here

I am wondering is there any tool to generate such a figure from a single bam or batch of bams?

Thanks, Junfeng

fragment ctDNA • 386 views
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