Tool:NCBI IgBLAST release 1.19.0 for immunoglobulin and T cell receptor variable domain sequences now available

Question

[PeterC_NCBI]

IgBLAST analyses nucleotide and protein immunoglobulin and T cell receptor variable domain sequences to find matches to the germline V, D, J and C genes, details at rearrangement junctions, the delineation of IG V domain framework regions, and complementarity determining regions. Get the latest release, which now handles an unrearranged J gene downstream of the VDJ rearrangement.

IgBLAST Home:https://ncbi.github.io/igblast/

Release notes: https://ncbi.github.io/igblast/rel/Release-notes.html

Download: https://ftp.ncbi.nlm.nih.gov/blast/executables/igblast/

[Jesse]

Thanks! What's this about unrearranged J genes? (Is that something that occurs some fraction of the time during recombination? I haven't heard of that before.)