Calculating probability of a false positive variant
0
1
Entering edit mode
2.2 years ago
drabiza1 ▴ 20

Ive sequenced 500 samples and performed variant calling. 3 of those samples are from the same individual. All the samples have a certain number of false positives. Some of the false positives are recurring and some are only seen once in the dataset. I found a certain variant that is called in the 3 samples from the same individual but in none of the 497 samples, but each of the 3 times it was identified, the variant was flagged as a false positive.

Is there some statistical method people use to identify the probability that this a false positive in this context?

VCF GATK Variant Calling • 393 views
ADD COMMENT

Login before adding your answer.

Traffic: 892 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6