Entering edit mode
18 months ago
abc
•
0
Hello, a question from a newbie:
how to do QTL analysis in mice? GEMMA gave me the following (.assoc.txt) output:
chr rs ps n_miss allele1 allele0 af logl_H1 l_mle p_lrt
1 UNC6 3010274 45 T C 0.753 -1.871575e+03 9.092954e+00 4.497885e-01...
I suppose I have to do the following:
1) to draw a Manhattan plot with 5×10^(−8) as a genomewide cutoff;
2) to make an 95% CI for each (?) significant SNP;
3) to search for and list the linked genomic regions.
A fantastic tool FUMA exists but only for GWAS in humans I guess...
Any suggestion on a tutorial or a tool for this task is appreciated.