At what threshold should module eigengenes needs to be cut to merge modules after dynamic tree cut?
0
0
Entering edit mode
16 months ago

Hello,

I have performed WGCNA on my mRNA expression dataset containing 709 genes and 10 samples. After dynamic tree cut I got 10 modules (including the grey module). However, I tried to merged the modules with similar expressions, I only got 3 modules (pink, brown, and black) at the ME dissThreshold value of 0.25. Should I proceed with these 3 modules or should I change the threshold value?

I have tried changing the values of MEdissThres, at 0.20 = same 3 modules at 0.10 = only my blue and red modules merged otherwise all other modules remain the same.

for your consideration, I have provided the following image files.

cluster tree

dendrogram

WGCNA • 505 views
ADD COMMENT

Login before adding your answer.

Traffic: 1354 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6