Map to get cpg probe id provided chr, start and end position
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9 months ago

Hi, I have this data from : https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE69894. Here is. a small subsample of the data:

chr start   end cpg_id  CD14_1  CD14_2  CD14_3  WholeBlood  Tonsil_1    CD14_4  ... CD8N_2  PBMC_2  CD4M_3  CD4N_3  CD8N_3  PBMC_3  Cortex_1    GanglionicEminence_1    Cortex_2    GanglionicEminence_2
0   chr1    10468   10470   chr1.1  0.95    0.46    0.95    0.95    0.91    0.95    ... 0.91    0.91    0.95    0.91    0.91    0.91    0.95    0.46    0.95    0.91
1   chr1    10470   10472   chr1.2  0.98    0.46    0.98    0.95    0.94    0.95    ... 0.94    0.91    0.95    0.91    0.91    0.94    0.98    0.46    0.98    0.91
2   chr1    10483   10485   chr1.3  0.98    0.46    0.98    0.95    0.93    0.98    ... 0.91    0.94    0.94    0.94    0.94    0.91    0.96    0.46    0.91    0.94

My aim is to find the corresponding Cg probe id from human methylation 450k (Hg19). I have information about chromosome and genomic coordinates which I obtained from 'The Infinium HumanMethylation450K v1.2 manifest file. There is a problem in mapping as there is no common column in both files.

PS: in short I have to map and find the cpg probe id related to chr, start and end position.

methylation genomic annotation TCGA • 535 views
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My aim is to find the corresponding Cg probe id from human methylation 450k (Hg19)

The link you provided above is for sequencing data (not arrays). And you want to map these sequence intervals/ID's onto a methylation array. Is that correct?

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Yes, I have to get the Cg probe ids corresponding to these chromosomes.

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