PLINK format file for BOLT-LMM
0
0
Entering edit mode
8 months ago
Apprentice ▴ 160

I would like to perform BOLT-LMM to assess the association of SNP with a quantitative trait. BOLT-LMM requires PLINK format files (bed, bim, fam) and imputed files (bgen, sample). Should I use direct genotype data typed from SNP arrays for the plink format files? Or should I use the imputed genotype data converted to plink format?

Also, do PLINK format files require quality control (e.g., removal of SNPs with MAF<0.01)? Please let us know.

BOLT-LMM SNP • 294 views
ADD COMMENT

Login before adding your answer.

Traffic: 1644 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6