Genes in open chromatin region

Question

[Chris]

Hi Biostars friends,

I have a questions about bulk ATAc seq that hope you can help. I use Diffbind to get the table below (differential accessibility regions) and then use ChipPeakAnno to annotate the peaks in the P column. Could I conclude that gene with positive Fold (D columns) is more open in diseased than in control (B column vs C column)? Thank you so much!