Eigen_phred_coding values interpretation
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3 months ago
Lukas ▴ 40

I have problem with understanding how to interpret Eigen_phred score.

I understand the main goal of this tool and know that score value would look similary to phred quality score:

Q=-10\ \log _{{10}}P.

But I haven't been able to find the P value. Only phred scaled score which I found something about the scaling is CADD_phred which has cutoff for pathogenic variations : CADD_phred > 20.

I am little but buffaled. I am not sure if i suppost to take same threshold for Eigen_phred or don't, because to me they are two different scores.

Can anybody please help me with the comfusion?

variation SNP annotation • 316 views
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Does anyone have at least primary citation on Eigen phred. Right now the main website for this score have been shut down, so I can't even check with authors of this score.

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