Issue with genetic QC sex check
0
0
Entering edit mode
5 months ago
kl ▴ 10

Hi,

I am doing a sex check on genetic data for a cohort I am working on, consisting of about 830 people. Most people seem to have incorrect sex assignment (around 560 problems). I have used plink QC and there were no people that showed excessive heterozygosity rates but the sex check seems bizarre really. Any suggestions on what may be going wrong would be much appreciated enter image description here

plink • 372 views
ADD COMMENT
0
Entering edit mode

After setting set-hh-missing, I have the following boxplot, where a F statistic of 0.91 corresponds to a female in my phenotypic dataset which doesn't seem quite right enter image description here

ADD REPLY

Login before adding your answer.

Traffic: 1380 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6