recessive model in saige
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4 months ago
ccagg ▴ 60

Is there a way to do a recessive model in the R package SAIGE for a GWAS? For example, in PLINK you might specify:

plink2 --bfile <input file>  -pheno <pheno file> --glm recessive --out <output> 

I have seen some papers referencing using SAIGE with a recessive instead of additive model (ex: DOI:10.1038/s41586-022-05420-7), but it is not clear to me how to do this reading the most recent SAIGE documentation

GWAS • 234 views
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