Tool:GW: fast genome browser and variant exploration tool

Question

[clealk]

Hello Biostars community,

Please check out our new tool, GW (Genome-Wide), a high-performance genome browser for the analysis and visualisation of aligned sequencing reads and data tracks.

GW facilitates rapid data rendering and addresses the memory limitations often encountered when visualising large genomic regions. This feature may be beneficial for researchers dealing with large copy-number variants or complex genome rearrangements.

GW has a user-friendly interface for navigating, annotating, and quantifying genomic data. It supports a wide range of built-in commands for data interaction, making it versatile for various analysis tasks.

*'Alignment-view' with a few data-tracks loaded

*An interactive view of the whole of chr8 rendered in 6-7s using a MacBook Pro M2, consuming <1Gb memory. Coloured arcs represent structural variants.

*Explore + annotate collections of variants using the 'image-view'

Highlights:

• Multi platform(MacOS, Linux, Windows, Android), CLI or Desktop apps available.
• Both dynamic and static modes of data visualisation.
• Customisation options for labels and visual themes to cater to user preferences.
• Tools for data examination and quantification, offering capabilities not available in other browsers (e.g. see 'filter' and 'count' commands).
• Integration with online genomic databases for data comparison.
• Stream VCF files to GW from other tools (e.g. bcftools) for convienient data exploration.

Documentation:

https://kcleal.github.io/gw/

Repo:

https://github.com/kcleal/gw

GW is still a work-in-progress and would welcome any feedback from the community to improve usability etc, so please get in touch if you would like to see additional features, or have any issues!