WGCNA preservation analysis
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5 weeks ago

I'd like to learn how to do a preservation analysis using WGCNA modules I've generated. However, the WGCNA tutorials and data seem to be offline.

https://horvath.genetics.ucla.edu/html/CoexpressionNetwork/ModulePreservation/Tutorials

Does anyone know where I can access the tutorial and the demo data?

https://web.archive.org/web/20211130024330/https://horvath.genetics.ucla.edu/html/CoexpressionNetwork/ModulePreservation/Tutorials/HumanChimp-Data.zip

Thanks!

WGCNA preservation • 225 views
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Entering edit mode
5 weeks ago
Michael 54k

This seems like a model case for why we need better sustainable bioinformatics data and services. I don't know the exact background behind this, but some things are obvious:

  • The original author (Horvath) no longer works for the institution (UCLA) where the project was developed,
  • He's now working for a private company (Altos) founded by Jeff Bezos
  • After he left, someone (possibly UCLA) deleted his group's web-space and is unable or unwilling to bring it back
  • Ratz: The important documentation is essentially lost (note the package is still available via the package manager)

Possibly you can find some of it or all here:

https://bioinformatics.stackexchange.com/questions/21885/where-to-access-the-wgcna-tutorial-documents-horvath-lab-site-down/

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