tools to increase hi-c resolution

Question

[J.F.Jiang]

Hi, all,

While numerous tools have been developed to predict high-resolution data from low-input samples, none of them can directly output files in .hic or .mcool formats.

It would be greatly appreciated if you could share these tools/resources.

Best, Junfeng

[GenoMax]

none of them can directly output files in .hic or .mcool formats.

Juicer (https://github.com/aidenlab/juicer/wiki ) outputs .hic files. Then you can use cooler (https://cooler.readthedocs.io/en/stable/ ).

[J.F.Jiang]

both Juicer and cooler could be applied to generate the .hic or .cool file, but none of them could be use to generate/predict high resolution matrix based on low resolution matrix, like EnHiC, HiCRes, or HiCplus.

However, existing tools can not output .hic or .cool files directly, which could not be use to downstream A/B, TAD analysis.

Therefore, I'm looking for software that can generate high - resolution evidence based on low - resolution files and directly output files in .hic or .cool format.