ARACNe-AP to viper aracne2regulon error
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Entering edit mode
2 hours ago
thasweer • 0

Hi,

I am performing a network analysis using ARACNe-AP. I was able to generate the consolidated network .txt file with 3 columns. Expression dataset matrix also available. While performing aracne2regulon function in viper R package as recommended by the authors,

my_regulon <- aracne2regulon(afile = "bootstrap_network_regulon.txt",eset = eset, format = "3col")

**following error was shown.**
Loading the dataset...
Generating the regulon objects...
Error in tapply(1:nrow(tmp), as.vector(tmp$tf), function(pos, tmp) { : 
  arguments must have same length
In addition: Warning messages:
1: In data.frame(tf = factor(tmp[, 1]), target = factor(tmp[, 2]),  :
  NAs introduced by coercion
2: In data.frame(tf = factor(tmp[, 1]), target = factor(tmp[, 2]),  :
  NAs introduced by coercion.

I tried to subset the gene expression matrix and re-do the analysis. It showed the same error. Please help me solve this error.

Thanks in Advance.

VIPER R ARACNe-AP aracne2regulon package • 35 views
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