Command-line interface, or CLI in brief, specifies how a user interacts with a program on the command line. Torsten Seemann wrote a good article on creating CLI. This blog post adds a few more suggestions. 1. Keep the backward compatibility of CLI as much as possible Backward compatibility here means users can upgrade and run a tool without changing the command lines they used in the past. This implies we should not remove or change the meaning of an existing …
go to blog
The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed...
go to blog
A couple of weeks ago I sat down for coffee with a pair of MGI representatives - American Region CEO Yongwei Zhang and Director, Global Business Development Damon Zhang. Since I hadn’t been at AGBT 2022 (my 2023 application already filed!). Yongwei and I had planned to try to catch up the next time he was in Boston area, so I braved our current subway issues (not one, but two major lines shut for extended maintenance!) and covered a range …
go to blog
The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed...
go to blog
The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed...
go to blog
This was once a guest post by Karol Estrada, who was a postdoctoral research fellow in the Analytic and Translational Research Unit at Massachusetts General Hospital and the Broad Institute of MIT and Harvard. It was written in memory of Laura Riba. We have briefly summarised her thoughts and findings from that post below. Karol … A Rare Variant in Mexico with Far-reaching Implications Read More »
go to blog
The common notion running through molecular biology is that the information present in DNA is transferred to RNA and then to protein. Back in 2010, researchers made a potentially ground-breaking observation. They found that within any given individual, there are tens of thousands of places where transcribed RNA does not match the template … Notes on the Evidence for Extensive RNA Editing in Humans Read More »
go to blog
In May 2019, it was reported in an article that over ten thousand sequence mismatches were observed between messenger RNA and DNA from the same individuals. More recently, three technical comments were published by Science surrounding this article. It was concluded that at least 90% of the Li et al. RDD sites are technical artifacts. … Questioning the Evidence for Non-Canonical RNA Editing in Humans Read More »
go to blog
A little while back, Razib Khan used data from 23andMe to explore his family’s genetic history. He previously published his findings and summarized them. Today, I’m going to fill you in on what he had to say! Khan was interested in genetics, anthropology, and history, mainly how we have changed the way lineages are marked … My Personal Genome: What Razib Khan Had to Say Read More »
go to blog
Alzheimer’s disease is a form of dementia that impacts the brain and results in memory loss. In recent years we have been able to study it and its risk factors to calculate the chances of you being affected by the disease. Today we are going to look at how that risk is calculated. Most people … Calculating your Alzheimer’s Risk Read More »
go to blog
At the annual Advances in Genome Biology and Technology (AGBT) conference held in Florida during 2012, there were many exciting announcements and developments in the world of DNA sequencing technology. An especially cool piece of news came from the team at Oxford Nanopore, the stars of our piece on cluster sequencing, about their (then) brand … Making Sequencing Simpler With Nanopores Read More »
go to blog
I agreed to make my 23andMe genotyping results available publicly as part of GNZ because I knew that the results were slightly dull, and I’m not majorly at high or low risk for any diseases. I was also very unsurprised to find out that I have blue eyes and that I was identified to … Testing Possibilities About My Ancestry Read More »
go to blog
It’s been over eight years since Oxford Nanopore presented the first ever nanopore sequencing data at the AGBT conference in February 2012, where they provided an overview of the hardware and software behind the GridION and MinION systems. Even today Oxford Nanopore could be seen as a dark horse. Their GridION platform is used … Cluster Sequencing with Oxford Nanopore’s GridION System Read More »
go to blog
It is usually thought that we can confidently say that if our genotyping results say that we carry a certain genetic variant, that we actually do carry that variant. However, why does this not mean that we can be confident about the prediction about disease risks? There are many risks and benefits associated with population … How Well Can a Screening Test Predict Disease Risk? Read More »
go to blog
Researching your family history is a fascinating experience. Even if you find out that your ancestors led very normal lives. Just being able to see the name and life milestones of your great-great-great-great-great (etc) grandmother is exciting. It’s amazing to be able to track your ancestry. But it can also be a confusing process. This … Best Genealogy Software Read More »
go to blog
The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed...
go to blog
The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed...
go to blog
I ran into an annoying problem last night and was quite steamed, but had the discipline to wait until morning to vent publicly about it. Now I'm more in a morose mood on the subject, not furious but still quite frustrated. The quick version of what happened is I'm belatedly trying to go through some nicely documented reproducible analysis code to explore some concerns I have with the analysis, and the code is working on an SRA entry -- and …
go to blog
The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed...
go to blog
Singular Genomics reported earnings last week and delivered an unpleasant surprise: inability of suppliers to make timely deliveries of key (but unspecified) hardware components have slowed G4 instrument production to a very slow crawl. Given the lively competition in the desktop short read space, this is a serious setback for Singular's commercial launch. Read more »
go to blog
The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed...
go to blog
The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed...
go to blog
The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed...
go to blog
The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed...
go to blog
The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed...
go to blog
The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed...
go to blog
The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed...
go to blog
The **Biostar Herald** publishes user submitted links of bioinformatics relevance. It aims to provide a summary of interesting and relevant information you may have missed...
go to blog
AGBT broke up a couple of weeks ago and I've failed to write anything here so far. It was frustrating not attending, but not registering for a meeting in February seemed prudent given the pattern of COVID waves - I hadn't considered (nor would have wanted to bank on) AGBT organizers reacting so well and rescheduling the meeting. It sounds like a number of attendees did catch the virus at the meeting -- though I'm presumably still quite protected by …
go to blog
Planet Feeds
Biostar Herald
Share bioinformatics resources from across the web.
125 posts - last
updated 2 days, 15 hours ago
Omics! Omics!
A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery
62 posts - last
updated 1 year, 2 months ago
Living in an Ivory Basement
Stochastic thoughts on science, testing, and programming.
71 posts - last
updated 1 year, 2 months ago
What You're Doing Is Rather Desperate
Notes from the life of a [data] scientist
17 posts - last
updated 1 year, 3 months ago
Bits of DNA
Reviews and commentary on computational biology by Lior Pachter
13 posts - last
updated 1 year, 3 months ago
Judge Starling
Dan Graur is the author of the book Molecular and Genome Evolution (2016). Dan Graur has a very low threshold for hooey, hype, hypocrisy, postmodernism, bad statistics, ignorance of population genetics and evolutionary biology, and hatred of any kind. This blog is a diary of peeves, dislikes, antipathies, annoyances, and random feelings of contempt. Rarely, do I have good things to say.
Following a silly letter from Scotland, I found it necessary to state very, very clearly that all the opinions expressed in this blog are my own and do not represent the views of either my academic employer or the current Secretary of the Flat Earth Society.
29 posts - last
updated 1 year, 3 months ago
KidsGenomics
Next-generation genomics for rare diseases and pediatric cancers
13 posts - last
updated 1 year, 4 months ago
GenomeRef
26 posts - last
updated 1 year, 11 months ago
Kevin's GATTACA World
My Weblog on Bioinformatics, Genome Science and Next Generation Sequencing
31 posts - last
updated 2 years, 6 months ago
Epistasis Blog
From the Computational Genetics Laboratory at the University of Pennsylvania (www.epistasis.org)
26 posts - last
updated 3 years ago
Genomes Unzipped
A group blog providing expert, independent commentary on the personal genomics industry.
20 posts - last
updated 3 years, 4 months ago
Opiniomics
bioinformatics, genomes, biology etc. "I don't mean to sound angry and cynical, but I am, so that's how it comes across"
10 posts - last
updated 3 years, 5 months ago
Blog – MacArthur Lab
Extracting useful information from large genomic datasets.
10 posts - last
updated 3 years, 11 months ago
Bioinformatics Bits and Pieces
10 posts - last
updated 4 years ago
Blue Collar Bioinformatics
Community built tools for biological data analysis
6 posts - last
updated 5 years, 2 months ago
In between lines of code
Biology, sequencing, bioinformatics and more
10 posts - last
updated 5 years, 4 months ago
Mike Love’s blog
7 posts - last
updated 5 years, 11 months ago
Bits of Bioinformatics
9 posts - last
updated 6 years, 2 months ago
Jermdemo
Mostly bioinformatics, NGS, and cat litter box reviews
25 posts - last
updated 6 years, 11 months ago
Getting Genetics Done
Getting Things Done in Genetics & Bioinformatics Research
25 posts - last
updated 7 years, 2 months ago
YOKOFAKUN
25 posts - last
updated 7 years, 3 months ago
Ewan's Blog: Bioinformatician at large
25 posts - last
updated 7 years, 4 months ago
opiniomics – has moved! www.opiniomics.org
opiniomics - has moved! www.opiniomics.org
1 post - last
updated 8 years, 3 months ago
Traffic: 2560 users visited in the last hour
Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by the
version 2.3.6
version 2.3.6