User: Mike

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Mike1.1k
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Posts by Mike

<prev • 205 results • page 1 of 21 • next >
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Comment: C: TCGA survival analysis: continuous vs discrete expression values
... Thanks again, yes there is difference in HRs with confidence intervals (upper/lower 95) HR HRlower HRupper 0.82 0.770 1.01 (discrete) 0.87 0.75 0.97 (continues) ...
written 1 day ago by Mike1.1k
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Comment: C: TCGA survival analysis: continuous vs discrete expression values
... Thanks Kevin for your help, I found a relevant article on this issue. Comparing continuous and discrete analyses of breast cancer survival information https://www.sciencedirect.com/science/article/pii/S0888754316300684 ...
written 1 day ago by Mike1.1k
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Comment: C: TCGA survival analysis: continuous vs discrete expression values
... nearly the same results using Z-scores data for discrete (logrankP= 0.02 ) & continuous model (logrankP= 0.00004 ). ...
written 1 day ago by Mike1.1k
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Comment: C: TCGA survival analysis: continuous vs discrete expression values
... Thanks Kevin, expression data is RSEM log2 and this is distribution. https://ibb.co/pbWBV0g Median expresssion values of this gene is 8.73 in 452 samples ...
written 1 day ago by Mike1.1k
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TCGA survival analysis: continuous vs discrete expression values
... Hi , I am trying to do a survival analysis for a gene using TCGA data, I did this by both ways, continuous expression value and discrete values (Low and high using median expression values). In both cases there is huge difference in p-values. Can anyone help me which way is better for survival anal ...
coxph cox model survival written 1 day ago by Mike1.1k
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Answer: A: PDB id to DSSP
... You can download all pre-calculated DSSP files from this link... https://swift.cmbi.umcn.nl/gv/dssp/ https://swift.cmbi.umcn.nl/gv/dssp/DSSP_5.html ...
written 15 days ago by Mike1.1k
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Comment: C: Survival analysis for a list of genes using TCGA data
... It works perfectly, thank you very much! ...
written 20 days ago by Mike1.1k
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Comment: C: Survival analysis for a list of genes using TCGA data
... Thank you very much, for RegParallel I need to upgrade my R (I have R version 3.3.3). ...
written 21 days ago by Mike1.1k
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Comment: C: Survival analysis for a list of genes using TCGA data
... Thanks Kevin, as always your help and codes are really very helpful. Yes I included all genes. you can see my comand: coxph(Surv(OS_MONTHS, Events) ~., data=merged_data [, c(2, 4:303)]) Is it correct? Sorry for again.. , what do you mean by test each independently and then construct a fina ...
written 21 days ago by Mike1.1k
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Survival analysis for a list of genes using TCGA data
... Hi all, I have a list of genes (around 300 genes) and I want survival analysis to find only significant genes. I am using TCGA RSEM normalized data in survival package using following command, but I'm not sure how to choose significant genes. coxph(Surv(OS_MONTHS, Events) ~., data=merged_data ...
coxph tcga survival analysis survival written 21 days ago by Mike1.1k

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Popular Question 7 months ago, created a question with more than 1,000 views. For clusterProfiler: Input file format
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Popular Question 14 months ago, created a question with more than 1,000 views. For GSVA analysis in R: How to use my geneset and expression data matrix in GSVA.
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