User: beausoleilmo

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beausoleilmo210
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210
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McGill University
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http://marcolivierbeau...
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5 months, 1 week ago
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2 years, 4 months ago
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b***********@gmail.com

I'm a biologist using statistics and bioinformatics.

Having multiple interest in the world, I want to share what I learn with my entourage. If you have any questions or ideas to share with me, I’ll be glad to hear about it.

glimpse(Interests) :

Biology Ecology Scientific popularization Education Art Music Poetry Philosophy Programmation Politics Your ideas

Posts by beausoleilmo

<prev • 94 results • page 1 of 10 • next >
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Comment: C: Difference Between Genotyping And Resequencing
... So are you inferring "reference genome thus => resequencing" or that you sequence first and then select a subset and "resequenced", but with a higher depth? Basically, is a reference genome necessary to say you are doing resequencing? ...
written 5 months ago by beausoleilmo210
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Comment: C: What is the definition of "multiply aligned" sequences compared to multiple alig
... Cool! But what about *multiply aligned* sequences? ...
written 5 months ago by beausoleilmo210
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What is the definition of "multiply aligned" sequences compared to multiple aligned sequence
... In [this article][1] they are talking about multiply aligned sequences. But, I can't find a formal definition of that. Is it simply the fact that the sequence was *multiplexed*? [Multiple sequence][2], intuitively would just be a collection of sequences. [1]: https://bmcbioinformatics.biomedc ...
sequence alignment dna written 5 months ago by beausoleilmo210
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Comment: C: Is whole genome pool-sequencing a reduced representation sequencing technique?
... For example, in RADseq, there is a size selection step so that there is "loss" of sequences that will never be sequenced (too large or too small). From my understanding, if you use illumina sequencing when the genome will be randomly sheared, it's going to be only parts of the genome that will be ...
written 7 months ago by beausoleilmo210
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Comment: C: Is whole genome pool-sequencing a reduced representation sequencing technique?
... What I'm usually seen is a 50X coverage for pool-seq on your reads. But since you don't size select, you just read different fragment length. Thus, you are not *sequencing* the whole genome and are therefor doing a reduced representation sequencing technique. I that correct? ...
written 7 months ago by beausoleilmo210
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Is whole genome pool-sequencing a reduced representation sequencing technique?
... I was reading a paper and it seems that they compare whole genome pool-sequencing with other technique saying that the the cost of reduced representation sequencing technique by reducing the amount of DNA to be sequenced. > In contrast to the whole-genome approach of Pool-seq, the cost savings ...
dna sequencing whole genome written 7 months ago by beausoleilmo210 • updated 7 months ago by h.mon21k
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Comment: C: Difference between Allele frequency spectrum and Joint allele frequency spectrum
... Cool! That's great! But if I read the axis on the graph, it's from 0 to 20 which makes 21 comparisons. > we projected the data down to 20 sampled chromosomes per population Where is the 21th comparison coming from? Also, is JAFS only on chromosomes or it can be on SNPs? In addition if you ha ...
written 7 months ago by beausoleilmo210
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Difference between Allele frequency spectrum and Joint allele frequency spectrum
... From what I understood, [allele frequency spectrum][1] is everything that concerns the frequency of all of the alleles studied in a population. It can be estimated with Tajima's D, theta, etc. But how is it different from the *joint* allele frequency spectrum? [1]: https://en.wikipedia.org/wi ...
population structure allele written 7 months ago by beausoleilmo210 • updated 7 months ago by Alice250
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Is there a way to construct a pedigree using RADseq data?
... I tried to find a paper showing how to do this, but I found nothing about ˙øw to create a genetic pedigree using neutral markers. Is there a way to construct a pedigree using RAD data? Most of the information I found is talking about *adding* a PED file for analysis, but not how to generate a pedi ...
pedigree rad sequencing written 8 months ago by beausoleilmo210
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Comment: C: What is population branch statistic (PBS)?
... Cool! They actually give a good description. Do you know why they say that it's more powerful do detect recent selection sweeps? > It should have power, for example to detect incomplete selective > sweeps, a type of selection that is highly relevant here and which > most other statistics b ...
written 10 months ago by beausoleilmo210

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