Question: Meta-Analysis Question using GEO2R
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gravatar for smectutor
6.6 years ago by
smectutor0
United States
smectutor0 wrote:

Im using data from GEO and the GEO2R online analysis tool provided by NCBI. The GEO2R analysis give adjusted P, P, t scores. I have 5-10 studies using the GEO2R tool.

Is there a way to combine all these scores and filter out only significant genes. 

Should I convert the P or T scores into Z scores and then I could follow the z=E(zk)/sqrt(K) to create a consensus z -score (union of genes). 

R script by GEO2R does does a log2 normalization. Do I do a z score after this step or before. 

 

Any suggestions would be appreciated.

 

micro-array R geo • 2.5k views
ADD COMMENTlink modified 6.5 years ago by Biostar ♦♦ 20 • written 6.6 years ago by smectutor0
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