Question: Meta-Analysis Question using GEO2R
gravatar for smectutor
6.6 years ago by
United States
smectutor0 wrote:

Im using data from GEO and the GEO2R online analysis tool provided by NCBI. The GEO2R analysis give adjusted P, P, t scores. I have 5-10 studies using the GEO2R tool.

Is there a way to combine all these scores and filter out only significant genes. 

Should I convert the P or T scores into Z scores and then I could follow the z=E(zk)/sqrt(K) to create a consensus z -score (union of genes). 

R script by GEO2R does does a log2 normalization. Do I do a z score after this step or before. 


Any suggestions would be appreciated.


micro-array R geo • 2.5k views
ADD COMMENTlink modified 6.5 years ago by Biostar ♦♦ 20 • written 6.6 years ago by smectutor0
Please log in to add an answer.


Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1433 users visited in the last hour