Question: Purifying selection M7 and M8 models
1
gravatar for RB
6.4 years ago by
RB20
Germany
RB20 wrote:

Dear All,

Can anyone suggest me how to utilize m7 and m8 models results to estimated purifying selection or relaxed constraints acting on your gene family.

Any other tutorial or methodology will also be helpful.

Thanks,

Reb

ADD COMMENTlink modified 6.3 years ago by Martombo2.6k • written 6.4 years ago by RB20
1
gravatar for Martombo
6.3 years ago by
Martombo2.6k
Seville, ES
Martombo2.6k wrote:

you can use the program codeml from the package PAML: http://abacus.gene.ucl.ac.uk/software/paml.html, manual: http://abacus.gene.ucl.ac.uk/software/pamlDOC.pdf

if you're new to programming you might find it easier to use the biopython implementation of PAML: http://biopython.org/wiki/PAML, it provides quite a user friendly interface to it and there are also examples you can follow.

ADD COMMENTlink modified 6.3 years ago • written 6.3 years ago by Martombo2.6k
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