I have used biomart quite a bit in the past to convert gene ID's or get dN/dS values, but I can't find any attribute in any obvious mart or dataset to retrieve background mutation rate.
This may just be a terminology problem, but I have dug around to no avail. Is there a way to access background mutation rate from biomart given a gene ID (say, TP53)?
Thanks very much for your help,
Marcus G.
What do you mean by background mutation rate? In what context are you working (e.g., cancer)?
Sorry - I should I have more specific. I want to compare mutation rate in cancer cells vs normal human mutation rates (specifically synonymous, silent substitutions).
Background mutation rate over the entire genome would be sufficient, but it would obviously be better if it is possible to get gene specific rates, as well.