HI.
I have a question. When finding the genes, How can I check the tumor related those genes?
If I find gene A, I want to check which tumor is related with gene A.
Sometimes I search the gene in the COSMIC website and check the study which use the gene.
But this method is so simply...so I want to know certain method.
One of the best approaches for a single gene or a few genes is to search the medical literature using PubMed.
Completely agree with Sean Davis, if there are few fusions to analyze the manual literature mining is the best choice.
If there are a plenty of fusions from deep RNA-Seq profiling, I would like to recommend our recent tool Oncofuse. It allows ranking gene fusions based on their probability of being a driver event in cancer. This ranking scheme includes several hallmarks of driver fusions in cancer (see this paper), such as an up-regulation of an oncogene's expression, functional signature, etc. This could be handy if your set includes novel fusions or there are too many fusions to check them manually.
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