Question

Does Hapmap2 Have Overlap With 1Kg?

1

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12.7 years ago

Ardmore ▴ 140

Does HAPMAP2 have overlap with 1KG? Or can we merge them together? I mean genotype.

hapmap genome • 2.3k views

ADD COMMENT • link updated 6.1 years ago by Biostar 20 • written 12.7 years ago by Ardmore ▴ 140

score 0 · Answer 1 · 2011-08-24

Depends on the population you're interested in, but simply said, yes there is overlap to some extend between the HapMap samples and the 1000 Genomes samples.

I know that for the CEU samples there is a mis-match between the HapMap genotypes and the latest 1000 Genomes release. Though, for the CEU samples the idea is to get the missing ones sequenced within the 1000 genomes on a later stage as well (depending on sample quality etc).

As for the merging I don't really understand what you mean. The 1000 genomes genotypes is actually a superset of the hapmap genotypes. So genotypes called in hapmap are also called in the 1000 genomes so there is not much to merge (or do I mis interpret your "merge" question?).