Question: building a phylogenetic tree with antibody protein sequences
2
gravatar for jellevandewege
3.5 years ago by
Netherlands
jellevandewege90 wrote:

Hi

I am trying to build a phylogenic tree with antibody protein sequences. The data I got are the same antibody sequences of various cells. The consequence is that there are mutation in the sequences. I want to compare it to the germline and create a tree to visualize the divergence between the sequences and the germline. Is there any software were I can input the protein sequences and germline to see the divergence to get a phylogenic tree? 

Thanks!

antibody phylogenic tree • 1.8k views
ADD COMMENTlink written 3.5 years ago by jellevandewege90

I've heard about the IgTree software with almost the same functionality as you've described. Still I haven't found a link to download it :)

ADD REPLYlink written 3.5 years ago by mikhail.shugay3.2k

Thanks!!! its exactly what I was looking for. Unfortunately I could not find a download as well.

ADD REPLYlink written 3.5 years ago by jellevandewege90

You can access the IgTree under MTA, you will have to send a request to senior author of the IgTree paper to get the tool..

ADD REPLYlink written 3.3 years ago by GP10
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