Question: how to get TF binding affinity from ENCODE narrowPeak or broadPeak files?
gravatar for liu4gre
5.9 years ago by
United States
liu4gre200 wrote:

I just learn to understanding ENCODE ChiP-Seq data for Transcription Factor binding. I know the narrowPeak format consists BED6+4 columns which is described in My question is:

1) does the region between chromStart and chromEnd mean the peak region (binding region)?

2) Does the signalValue mean the binding affinity?

3) Is it good to compare this value across cell lines to see the difference?

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