Question: how to get TF binding affinity from ENCODE narrowPeak or broadPeak files?
3
gravatar for liu4gre
4.6 years ago by
liu4gre200
United States
liu4gre200 wrote:

I just learn to understanding ENCODE ChiP-Seq data for Transcription Factor binding. I know the narrowPeak format consists BED6+4 columns which is described in https://genome.ucsc.edu/FAQ/FAQformat.html#format12. My question is:

1) does the region between chromStart and chromEnd mean the peak region (binding region)?

2) Does the signalValue mean the binding affinity?

3) Is it good to compare this value across cell lines to see the difference?

ADD COMMENTlink modified 4.6 years ago • written 4.6 years ago by liu4gre200
Please log in to add an answer.

Help
Access

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by Biostar version 2.3.0
Traffic: 1644 users visited in the last hour