I applied Oncofuse to annotate fusion genes from DNA-seq and would like to determine if the fusion is in-frame or not. Oncofuse provided 5_FRAME (frame of translated 5'FPG), 3_FRAME (frame of translated 3'FPG) and FPG_FRAME_DIFFERENCE (difference in 5' and 3' FPG frames). Their values are 0, 1 and 2. May I ask what these values mean? How do I interpret the FPG_FRAME_DIFFERENCE? Thanks.