What is minimum limit for assigning interval during imputation using IMPUTE2?
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9.3 years ago
d0ct0r ▴ 30

IMPUTE2 website recommend imputation in region less than 10 Mb to get more accurate predictions. But I need to know what is the minimum value I can set for the procedure. I tried with a distance of 50 Kb (+250 Kb buffer) and I got 99.9 percent concordance. But I am doubtful if that small region imputation will be accurate. The imputed region had less than 200 SNPs. Anyone with experience in this please let your views and suggestions. thank you

snp gwas imputation impute2 • 1.6k views
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