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9.3 years ago
d0ct0r
▴
30
IMPUTE2 website recommend imputation in region less than 10 Mb to get more accurate predictions. But I need to know what is the minimum value I can set for the procedure. I tried with a distance of 50 Kb (+250 Kb buffer) and I got 99.9 percent concordance. But I am doubtful if that small region imputation will be accurate. The imputed region had less than 200 SNPs. Anyone with experience in this please let your views and suggestions. thank you