Prediction Transcription Factor Families

Question

[Kurban]

Hello for all,

Is there any way or tool or database to predict Transcription Factor Families according to their amino acid sequences (by the way, they are animal TF sequences)?

Any suggestions would be appreciated.

[dago]

Prokaryote or eukaryote?

[Kurban]

Hello @dago,

It's eukaryote.

Answer 1

[UnivStudent]

You can identify putative DNA binding domains (DBDs) using tools like Pfam, InterPro, hmmscan in HMMER. Since your TFs are eukaryotic you can also use the Protein Scan tool in Cis-BP to identify whether these have DBDs and if they have sequence specificities.