how to identify mutations transmitted from parents to child?
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8.5 years ago

Hey i have detected mutations detected in both parents

how to identify mutations effecting child..& which are acting as carriers for disease.

Is thre any software to detect mutations for a given sequence data of both parents and child.

Thanks

mutation • 1.5k views
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Do you have the child's genotype data? If so, you can use those de-novo mutation detection tools to do it

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You could phase the variant calls (using GATK's PhaseByTransission) and pick variants with a specific inheritance pattern.

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