I downloaded GBM microarray data from TCGA website. When I open the expression files, I found two columns, the first one is gene symbol, the second is "log2 lowess normalized (cy5/cy3) ". Then I open the sdrf.txt file to find the explanation to the second column. It is said that cy5 is GBM and cy3 is various. I'm wondering what is "various" mean. Is it the normal tissue or something else? "log2 lowess normalized (cy5/cy3)" means the ratio between GBM and normal tissue or just GBM mRNA expression level?