I have emailed the folks at OpenSNP for some clarification, but I figure those here may know, and certainly if I get any information back from OpenSNP I will post it up in this thread.
I have recently starting doing some research using OpenSNP.
Does anyone know if the information on there is from GRCh37 or GRCh38?
I ask because for example, SNP rs1000016 is position 235690982 in GRCh37 and 234782338 in GRCh38.
Yet in the OpenSNP database, when I pull up the SNP, It shows "Human GrCh37/hg19" in the Genome Browser Window, but the position given for the SNP is from GRCh38. https://opensnp.org/snps/rs1000016
When you get a aDNA report from 23andMe or Ancestry, it uses GRCh37. So in trying to do analysis of these reports against data on OpenSNP I run into issues. I have also seen that SNPedia has the same location as OpenSNP (GRCh38).
Just trying to figure out the best way to handle this and do my analysis.
Here is a response I got from OpenSNP: