Question: Viable pathway tool for T-Cell activation pathway identification
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gravatar for onspotproductions
3.5 years ago by
United States
onspotproductions120 wrote:

I have a list of genes that are of high expression in activated T-cells. I am looking for a good pathway tool to either identify the list of genes and their connections, or find a single pathway for one of the genes. So far I have had minimal luck using DAVID and reactome. I did however get some results through babelomics snow, I am just unsure how to continue with the data it has generated. I have looked through KEGG and biocarta as well, with minimal success. We are looking for protein effects on RNA processing of other target genes. Strings does a good job in showing relations, however we are less concerned with protein-protein interaction.

ADD COMMENTlink modified 3.5 years ago • written 3.5 years ago by onspotproductions120

I'm still confused about what you have and what you want.  Can you clarify what you are trying to do?

ADD REPLYlink written 3.5 years ago by Sean Davis25k

Yes. We have a list of 13 proteins that showed high expression in Activated T-Cells vs. non activated T-cells. We are attempting to determine how these 13 proteins fit into a T-Cell activation pathway. We want to look at how the proteins act upon the rna, not on each other. 

ADD REPLYlink written 3.5 years ago by onspotproductions120
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