Best tools for gene analysis, annotation, phylogenetic analysis and comparative tool.

Question

[bjevitha]

Hi, good day everyone!

Please help me to suggest Tool/ Software/ Server that might help my research that based on gene analysis.

• Gene annotations
• Comparative gene analysis tools (Skin genes)
• Phylogenetic analysis
• To find the mutated location in the mutated gene

Basically my research is comparing mutated skin genes and normal skin genes.

Thank You Very Much!

Jevitha Bsc Bioinformatics MSU, Malaysia

[indhupriya.b]

Hi,

You can try eSkIN www.persistent.com/eskin) a computational platform for skin research. eSkIN has manually curated knowledgebase on genes associated with skin and helps in the prioritization of skin pathways (Pathway enrihemnt analysis) based on your data. To register: http://eskin.igib.res.in/#/register We are also hosting a webinar on Skin centric analysis of biological data using eSkIN. To register for the webinar: http://eskin.persistent.co.in/#/registerWebinar

Answer 1

[Brian Bushnell]

For alignment, in this specific case, I recommend... hmmmm...

Perhaps BBMap. It's particularly good for finding long indels and other major mutations by mapping with fairly low identity.

For other cases, it's entirely possible that I might recommend something else.