I am trying to run aracne in geworkbench 2.5.1.
It successfully run on some normalized gene expression data belong to cancer patients.
However when I try to run it on normalized gene expression data of normal tissue, I get the error message that "the aracne run resulted in no adjacent genes, consider relaxing your thresholds". I have tried different thresholds but only when I choose p-value=1, I can get some results.
Can any one give me any explanation about this problem and the probable reasons?
Thank you in advance