Network Component Analysis (Nca) Implementation?

Question

[Timmyt]

Hi biostar community,

I'm looking for a software implementation of the Network Component Analysis (NCA) method proposed here:

http://www.pnas.org/content/100/26/15522.abstract

I ran across a 2008 java implementation, but it looks like the project is dead:

http://code.google.com/p/ncajava/wiki/PageName

Hoping someone can recommend a good implementation.

Any help/guidance is much appreciated,

Tim Wilson

[Manu Prestat]

This is very interesting. I did not know this method.

Answer 1

[Gjain]

Hi Tim,

There is a matlab implementation for NCA. A more updated(2007) version can be found here.

There are 2 papers on this topic that explain NCA, just in case:

1. Network component analysis: Reconstruction of regulatory signals in biological systems
2. Network Component Analysis (NCA) by Falko Krause

I hope this helps.