I'm currently studying computer science and I wish to specialise in bio-computing, I need to work on a project and write a dissertation for my degree and I was wondering if I could get some help in narrowing down which topics would be realistic. I have a basic background in biology and I'm interested in epigenetics so I wish to somehow incorporate that into my project. A software engineering based project would be preferred.
My current idea is to make a (visual?) tool based on Bayesian networks to predict likelihood of disease or expression of a gene associated with a disease based on already known links with e.g. high levels of methylation. Firstly is there much data available about these sorts of links? Is there a need for a tool like this? Is it feasible to estimate the likelihood of disease or at least suggest genes to target for study?
My second idea is also to create a tool to make a Boolean network model of gene regulatory networks and use methylation data to influence the GNR. Would there be a useful application of this in the real world?
I know very little details about both topics so I'm hoping this post hasn't just been a string of key words but actually makes sense!
Thank you in advance!