Among the many technologic developments improving the efficiency of biological processes is the RBS Calculator, a tool that predicts translation initiation rate and protein expression in bacteria. Developed by Howard Salis, the RBS calculator has the ability to predict the translation initiation rate for each start codon in an mRNA sequence. The tool then uses this information to design the ideal ribosome binding site to achieve optimal translation rate, and thus control protein expression. Genome Compiler has recently embedded the RBS Calculator into it's all-in-one gene designer software, increasing the availability of the tool for academia and industry use.
Read more about this powerful tool.