Bioinformatics in a dynamic, interdisciplinary research group studying the genomic basis of neurodevelopmental disorders
The Kruer lab seeks to understand the molecular mechanisms that lead to neuromotor disability. Our work is fundamentally translational and highly interdisciplinary. We apply a broad variety of approaches, encompassing genomics, bioinformatics, human molecular genetics, cell biology & biochemistry, mouse models of disease, high-throughput genetic screens, and neuronally-differentiated iPSCs (www.kruerlab.org). Current research projects include disease gene discovery in pediatric movement disorders and an international collaborative study of cerebral palsy genomics.
The lab is well-equipped for cutting-edge neurogenetics research and is housed in a newly constructed research building in the midst of the rapidly growing downtown Phoenix biomedical campus. Postdocs will be responsible for the analysis and integration of whole exome and whole genome datasets, genomic copy number analysis, and the development and application of new statistical and computational methods focused on the detection of gene-gene and gene-environment interactions, deep phenotyping including advanced neuroimaging (morphometry, perfusion-weighted and diffusion tensor imaging, and functional MRI), and network/pathway analysis. Our lab allows postdoctoral candidates to work within a thriving interdisciplinary collaborative network and to develop projects with direct relevance to human neurological diseases.
The University of Arizona Phoenix is home to a vibrant research environment within the sixth largest city in the United States. Our thriving genetics community includes ample opportunities for collaboration, with particular strengths in next-generation sequencing, bioinformatics, genetic screens, clinical genetics, proteomics, genome editing, mouse genetics and model organisms.
Phoenix combines diverse cultural and entertainment venues with a favorable cost of living, spurring continued growth and investment in the community. Our year-round sunshine and array of urban village communities surrounding the campus afford ample opportunities to find a comfortable home for both individuals and families.
Interested candidates should contact PI Michael Kruer at kruerm@email.arizona.edu
