Question: Can a locally created database be used instead of NR in I-TASSER?
gravatar for Neha shri
3.3 years ago by
Neha shri30
United States
Neha shri30 wrote:

Dear all,

                 I have generated a database of protein sequences and selected a few sequences from it based on some criteria. Now i would like to model these selected sequences and see if they folded into the native structure of a protein. The protein (native)  shares a sequence similarity of 40% with all the sequences in the database.

              As i- tasser uses NR database from pdb to generate sequence profile for the target sequence,will it be theoretically correct to use a locally created database of proteins instead of NR database.

Hope i am able to make myself clear. Please ask for more clarity if required and suggest if the idea is feasible or not. Thank you

ADD COMMENTlink modified 3.3 years ago • written 3.3 years ago by Neha shri30
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