Off topic:Concentrating method for TruSeq lib prep in microRNA sequencing

Question

[CandiceChuDVM]

Hi all,

We are planning to submit our microRNA samples that we isolated from biofluids (serum and urine).

We use column-based isolation methods and we usually elude our samples in 50ul of RNase-free water; however, the requirement for sample submission (10-15 ng of microRNA in 5 ul) is way concentrated than our samples.

I was wondering how can we concentrate our microRNA samples?

Any suggestions are appreciated. Thanks!