23andMe SNP data does not correlate with UCSC. What am I doing wrong?
1
0
Entering edit mode
8.2 years ago
sfcarroll ▴ 80

23andMe provide SNP information via their API, examples below.

# Updated: 2014-07-23
# index is a key for the /genomes/ endpoint (2 base pairs per index).
# strand is always +1.
index snp chromosome chromosome_position

316 rs1000219 10 54442734
317 rs1000220 4 16621729
318 rs10002203 4 186504624
319 rs1000221 15 89627396
320 rs1000222 4 140587985

When I take one of these SNP entries and cross-check against UCSC, I am getting different coordinates. For example, with hg38: rs10002203 at chr4:185583220-185583720

How can I cross-reference 23andMe SNPs against an assembly?

UCSC 23andme • 2.0k views
ADD COMMENT
3
Entering edit mode
8.2 years ago
abascalfederico ★ 1.2k

Coordinates chr4:186504624 are for build 37. In build 38 rs10002203 has coordinates: chr4:185583470.

If you click on the SNP within the browser you will be able to see the exact coordinates.

ADD COMMENT

Login before adding your answer.

Traffic: 2027 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6