I have a hybrid assembly (illumina + pacbio subreads - DBG2OCL assembler) for an 1.5Gb eukaryotic genome, and now I'm in doubt if I should quiver this assembly or not.
Once, as I read, quiver calls consensus based on the pacbio quality of the aligned subreads to the draft genome, what it would do to the regions that are covered only by my Illumina contigs in the hybrid assembly?
Does it make sense to run quiver in a hybrid assembly at all?
Thanks a lot for the help! =)